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Product Description
L-Alpha glycerylphosphorylcholine (alpha-GPC, choline alfoscerate) is a key brain cell membrane phospholipid and cholinergic precursor. AlphaGPC is an important neurotransmitter and phospholipid precursor providing support for age-related decline in cognitive function, memory, and cerebrovascular health. AlphaGPC is a source of choline for the synthesis of the neurotransmitter acetylcholine, with a greater ability to penetrate the blood-brain barrier than conventional choline sources. In Europe,alphaGPCit is prescribed to treat Alzheimer’s disease. In the United States,AlphaGPC is an over-the-counter nootropic dietary choline supplement, intended to improve memory and cognitive function, and as well as encourage muscle building.
Item name: Alpha GPC powder
Chemical name: L-alpha-Glycerylphosphoryl choline; Choline alfoscerate
CAS NO.: 28319-77-9
Molecular Formula: C8H20NO6P
Molecular Weight: 257.22
Standard: USP29 Pharm. Grade and Food grade
Assay(anhydrous basis): 99%, 50%
Test Method : HPLC
Appearance Colorless clear viscous liquid & white powder
Packing 1kg/bag, 5kg/bag, 25kgs/drum (standard packing)
Quality standard
|
Items |
Specifications |
|
Assay (by HPLC) |
98.5%~101.5% |
|
Appearance |
White powder, neutral odor, very highly hydroscopic |
|
Identification (by TLC) |
NMR conforms to standard |
|
Specific rotation[α] |
-2.4°~ -2.95° |
|
Solubility(H2O,10% w/v) |
Clear |
|
Stability |
Dry and light protected storage; stable under normal usage. |
|
Solvents residue (Ethanols) |
≤1.0% |
|
pH |
4.5~6.5 |
|
Chloride (Cl) |
≤0.02% |
|
Sulfate |
≤0.02% |
|
Heavy metals (as Pb) |
≤10ppm |
|
Phosphate Ion |
The color of solution not stronger than the control solution (5ppm) |
|
Water content |
≤2.0% |
|
Total impurity |
≤2.0% |
|
Single impurity |
≤0.5% |
|
Solvents residue (Ethanol) |
≤1.0% |
|
Related substances(TLC) |
Single spot |
Function:
1) Alpha GPC improve memory and cognitive performance in patients with Alzheimer's dementia.
2) Alpha GPC improve memory and learning ability.
3) Alpha GPC help brain recovery following surgery, injury and coma.
4) Alpha GPC counter the age-related loss of nerve cells and fibers in the brain.
5) Alpha GPC protect the brain and other organs against toxic waste buildup.
6) Alpha GPC support patients recovering from cerebral ischemic attack.
7) Alpha GPC Increase the release of dopamine, plays a major role in parkinson's disease.
8) Alpha GPC counteract brain aging by increasing cholinergic receptor sites,increasing nerve growth factor receptors in the brain, restoring the bioavailability of acetylcholine,slowing down undesirable structural changes in the brain.
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